Alan J. Grodzinsky, ScD
Research Highlights
Musculoskeletal tissue engineering, mechanobiology, and cell signaling pathways that are upregulated in models of inflammatory injury in vitro and in vivo.
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Research:
Our group focuses on problems motivated by diseases of the musculoskeletal system including arthritis, connective tissue pathologies and, more generally, the molecular biology and biophysics of the extracellular matrix (ECM). We have developed experimental methods and theoretical models to characterize the mechanobiological behavior of cartilage, tendon, and other connective tissues subjected to compressive, shear and impact overload in vitro and in vivo.
Biography:
Professor Alan Grodzinsky attended the Massachusetts Institute of Technology as an undergraduate, graduating in 1971 with a Bachelor’s and Master’s in Electrical Engineering. He worked with James Melcher (EECS) during his graduate studies at MIT, earning a Ph.D. in 1974 for his work on membrane electromechanics. Grodzinsky has received numerous awards including the NIH Merit Award and is a Founding Fellow of the American Institute of Medical and Biological Engineering.